- SeriesADDA High Speed LC/MS
Built for Discovery™ ADDA High-Speed Dual Arm Autosampling System The ADDA system is a dual-arm, high-speed autosampler that provides ADME discovery scientists with the fastest high-quality sample delivery platform available for LCMS. At 8 seconds per sample in trapelute mode, and with 8 unique injection ports, the ADDA system is a comprehensive system designed for the Discovery lab. With the ADDA system, permeability, transport, metabolic stability and drug-drug interaction screening assays can be rapidly turned around with a single mass spectrometer system, saving critical time in the drug discovery process. Special Features of the system – Multiple autosamplers in one The system achieves its speed and flexibility with 2 high-speed, high-accuracy robotic arms, each equipped with a syringe and four injection ports. Batches can be submitted to use either one arm or both arms simultaneously. The plumbing can be set up on a per-injection-port basis, allowing up to 8 different gradients and columns to be left on the system. Four onboard valves simplify the plumbing for the system. Testing with multiple chromatographic setups, direct infusion and high-speed trap and elute experiments can be performed in a completely automated fashion. Alternatively, if two different scientists are using the system, they can run independent experiments easily by each using a different arm. No Reformatting With a capacity for up to 12 plates on a single deck (96-well or 384-well, deep or shallow are supported), the ADDA system has instant access to every sample, meaning that sampling across plates from a time course study is rapid and efficient – no reformatting step necessary. All-in-One Software, Multiplexing, and Multi-Batch Automation The ADDA software was developed by Sound Analytics LLC, makers of the industry-standard DiscoveryQuant™ software for AB SCIEX instruments. It offers excellent instrument control along with the ability to access MSMS conditions from a central database, and interleave various LC modes on the fly. Intuitive visual interfaces simplify sample setup and batch building. Full multiplexing support is available to multiplex gradient runs. The software effortlessly switches batches to different arms and different injection ports, allowing for automated overnight runs of many different batches of different chemistries without pause. The runs can then be analyzed using the DiscoveryQuant™ Analyze software, making it easy to integrate all peaks and export them to Excel or another software system.