Saint-Gobain Performance Plastics

• designs2D and 3D

Saint-Gobain manufactures single-use bags for cylindrical tanks that offer broad chemical compatibility for safe handling of biopharmaceutical liquids. The bags are constructed of multi-layer films optimized for bioprocess production, allowing for easy integration into single-use process applications. FeaturesBenefits: • 2D and 3D designs • Top or bottom drain • Recirculation loop • Needle-free sampling port • May be used with sterile welder • Animal-derived component free • Validated using widely accepted test methods Typical Applications: • Buffer and media storage • Bioreactor feed and harvest • Intermediate product hold • Chromatography feed • Fraction collection • Final product hold

• Integrated handle(2 liter – 20 liter)

Saint-Gobain single-use bags provide broad chemical compatibility for safe handling of a wide range of biopharmaceutical liquids. Constructed of multi-layer films optimized for bioprocess production, the bags allow for easy integration into single-use process applications. FeaturesBenefits: • Integrated handle (2 liter – 20 liter) • Integrated hanging capability • Needle-free sampling port • May be used with sterile welder • Animal-derived component free • Validated using widely accepted test methods Typical Applications: • Buffer and media storage • Bioreactor feed and harvest • Intermediate product hold • Chromatography feed • Fraction collection • Product sampling • Final product hold

Sani-Tech® EZ Top® container closures are manufactured from high-purity, biopharmaceutical-grade, platinum-cured silicone elastomers. These components and assemblies provide an aseptic seal for handling various highly sensitive fluids in biopharmaceutical applications. The Sani-Tech® EZ Top® container closure allows you to easily retrofit your existing glass and plastic carboys, glass solution and media bottles, and stainless steel vessels for aseptic fluid transfer, sampling or sealing. These systems can be supplied in a wide range of sizes and customized features, including multiple ports and coding identification. FeaturesBenefits: • Provides complete aseptic container closures • Biopharmaceutical-grade silicone elastomers and thermoplastics • Autoclavable and sterilizable • Custom configurations with multiport orientations • Utilizes SIB® (smooth inner bore) technology to ensure crevice-free construction • Meets USP Class VI, European Pharmacopoeia 3.1.9 and FDA criteria Typical Applications: • Glass and plastic carboys • Solution and media bottles • Stainless steel vessels • Laboratory equipment and apparatus • Experimental procedures

Sani-Tech® ultra-pure platinum-cured silicone stoppers outperform standard neoprene and rubber stoppers in critical laboratory and process applications. These long-life silicone stoppers are fully autoclavable and sterilizable and will not crack, spallate or invoke particle migrations that can cause process or product contamination. All Sani-Tech® silicone stoppers can be supplied in a solid configuration or with cored holes for use with dip tubes or vents. Custom identification markings can also be supplied to help differentiate supply lines. FeaturesBenefits: • Ultra-pure biopharmaceutical-grade silicone stoppers • Unsurpassed surface smoothness • Resists cracking and spallation • No particle migration • Autoclavable and sterilizable • Imparts no taste or odors • Custom identification and color options • Meets USP Class VI and FDA criteria Typical Applications: • Solution and media bottles • Glass and plastic carboys and vessels • Process and storage procedures • Laboratory apparatus

EZ Top® container closures are one-piece units consisting of tubing and an overmolded stopper. Economical and designed for single use, these closures eliminate contamination that can occur with repeat-use closures and play a key role in the reduction of cleaning and assembly time. One-piece construction – which employs a thermal bond between tubing and stopper – eliminates product loss and contamination due to loose connections. EZ Top® container closures are made from C-Flex® pharmaceutical-grade resin and tubing to ensure an unobstructed fluid path and extremely low levels of extractables, and to provide an elastomeric seal against glass, plastic and metal surfaces. They are easily used with sterile connecting devices and thermal tubing sealers, and are autoclavable. Standard configurations fit a wide variety of glass, plastic and stainless steel containers, from 60mL vials to 20L carboys. EZ Top® container closures are pre-packaged in units of 10. Containers are sold separately. Caps are also sold separately (in units of 10) and are specifically designed for use with EZ Top® container closures. Custom designs for port configurations, tubing dimensions, materials, sizes and packaging are available upon request. FeaturesBenefits: • Economical single-use closures reduce cleaning and assembly time • Eliminates contamination issues with repeat-use closures • Provides elastomeric seal against glass, plastic and metal surfaces • Made from C-Flex® pharmaceutical-grade resin and tubing • Integral one-piece design eliminates product loss and contamination • Unobstructed fluid path • Extremely low levels of extractables • Custom options available upon request Typical Applications: • Glass and plastic carboys • Solution and media bottles • Stainless steel vessels • Laboratory equipment and apparatus • Experimental procedures

BarbLock® ultra-secure retainers are the most advanced design available in today’s demanding connective applications. When it comes to retaining flexible tubing and hose onto barbed fittings, BarbLock® retainers are the only system with a full 360° radial crimp behind the barb and 360° of compression directly over the barb’s ridge. BarbLock® retainers have become the standard in many industries, including biopharmaceutical, medical and laboratory, because they solve inherent leak path problems in sensitive and demanding applications. The retainer uses no adhesives or solvents, is ideal for systems transferring delicate liquids or gases, and is quick and easy to assemble, saving valuable time. FeaturesBenefits: • Replaces inconsistent and leak-prone cable ties and traditional clamps • Compatible with all flexible tubing materials • Provides 360° radial crimp behind the barb • Supplies 360° compression over the barb and full dynamic retention • Eliminates solvent bonding, ultraviolet bonding and toxic adhesives • Constructed with USP Class VI materials • Quick and easy to assemble Typical Applications: • Biopharmaceutical transport systems • Flexible tubing and hose retainers • Disposable assemblies • Medical equipment and apparatus • Quick connects