AdvantaPure, Div. of NewAge Industries, Inc.

United States

An alternative for sanitary connections is now available from AdvantaPure.Overmolded Tri-Clamp Ends for PVC, TPE, and TPR tubing and hose. Injection molded from USP Class VI Hytrel or polypropylene, Overmolded Tri-Clamp Ends feature Tri-Clamp and mini Tri-Clamp styles up to 1-12". Overmolded Tri-Clamp Ends greatly reduce bioburden entrapment situations associated with barb-type fittings.They cost less than silicone counterparts, making them an attractive option for pharmaceutical, medical, surgical, food, beverage, and dairy applications.KEY FEATURESInjection molded from USP Class VI Hytrel and polypropylene materialsCertified free of animal-derived ingredientsEnds are permanently attached using a thermal process no leachable adhesives are involvedSmooth interior for excellent flow and performanceReduces entrapment issuesProvides a sanitary connection for thermoplastic tubing and hoseExcellent component for single-use applicationsLess costly than similar components of siliconeAvailable in both Tri-Clamp and mini Tri-ClampSizes range from mini through 1-12" Tri-ClampEasily sterilizedcleanedHytrel molds directly to PVC; polypropylene molds directly to TPR and TPE tubing such as AdvantaFlexAssemblies made to orderDocumented quality control

Clear identification, cleanliness, sterilizability, and permanence are offered with AdvantaPure's AdvantaLABEL tagging system. AdvantaLabel eliminates the issues involved with old-style metal, plastic, or even paper tags. Since the label is sealed to the hose in clean silicone, it can be either steam sterilized (SIP) or chemically cleaned (CIP) many times without degradation of the label. AdvantaLABEL is custom configured to meet your specific needs part number, manufactured date, planned replacement date, or any specific information you deem critical. Contact your AdvantaPure representative today to see how AdvantaLABEL can solve your hose tagging needs at 1-888-755-4370.O.D. mounted to reinforced silicone hoses does not contact material flowPermanently vulcanized siliconeCertified free of animal-derived ingredientsEasy to read label remains bright white after repeated sterilizationAutoclavableZero entrapmentHandles clean-in-place (CIP) or steam-in-place (SIP) processesCustomer supplied text is application specificAdd color striping for quick line identification 10 standard colors available*Field installation methods available

Eliminate production stoppages for sterilization, reduce the risk of contamination, and increase efficiency by incorporating Single-Use Systems from AdvantaPure. Single Use Systems, or SUS, simplify cleaning validationsuse once and discard. Each system is custom made using platinum-cured, Class VI silicone tubing and hose or AdvantaFlex Class VI biopharmaceutical grade tubing. Add fittings, stoppers and container closures, filters, bottles, labels and tracking options, and other components.Custom manufactured and assembled from a variety of componentsReduces end-user assembly labor expense and timeReduces cross contamination risksSaves energy and resource costs by eliminating cleaning and autoclavingReduces production downtime by eliminating certain cleaning validation requirementsProvides flexibility and speed in facility designsystem redesigns are implemented faster than with hard pipingLess costly process development and design compared to systems of hard pipingAssembled and packaged in Class 7 (Class 10, 000) ISO-certified clean roomsAvailable with validated sterility assurance of 10-6 per ISO 11137 method VDmax 25Documented lot traceable with identification on bagsDocumented quality controlExperienced engineers available for technical assistanceTubing and molded connections provide a single, animal-derived ingredient-free material contact surfaceComplete validation package available upon requestOptional RFID tags easily attach to assemblies for identification purposesprovide reliable electronic data storage and current status of assemblies from inception to disposalThe silicone and thermoplastic elastomer compounds used to make Single-Use Systems have a Master File with the U.S. Food and Drug Administration

Supplied as silicone fittings attached directly to silicone tubing or hose, AdvantaPure's Molded Silicone Assemblies are well-suited for applications involving aseptic transfer, sterile processing, and other critical applications in the pharmaceutical, biomedical, and high purity industries. The assemblies reduce installation time, improve cleanliness, and retain the many benefits of silicone.Eliminates entrapment issues and leaks associated with barb-type fittingsProvides a smooth inner surface with a seamless transitionOffers consistent interior dimensions for maximum flow ratesReduces end-user assembly timesarrives ready to installNo product contact with metallic materialsRetains silicone's temperature resistance: -100F to 400FExtremely flexibleSterilizable by CIP, SIP, and autoclave processesCertified free of animal-derived ingredientsImparts no taste or odor to critical streamsCleanroom manufacturedSealed in clear polybags during manufacturing process to ensure cleanlinessDocumented lot traceable with identification on bagsDocumented quality controlThe compound used to make Molded Silicone Assemblies has a Master File with the U.S. Food and Drug Administration

Manufactured from USP Class VI, platinum-cured silicone elastomer or from AdvantaFlex biopharmaceutical grade TPE, AdvantaPure's BioClosure Systems offer the utmost in purity. They're biologically safe and work with vessels of glass, metal or plastic. Stoppers, caps, inserts for True Unions and GL45's, and other styles, with or without tubing, are available.Ideally suited for pharmaceutical, biotech, and laboratory environmentsSilicone elastomer meets USP Class VI, FDA CFR 177.2600, ISO 10993, European Pharmacopoeia 3.1.9, and other industry standardsAssembled and packaged in a Class 7 (Class 10, 000) ISO-certified clean roomBoth silicone and TPE are certified free of animal-derived ingredientsDocumented lot traceableFor single or repeated use sterilizable through autoclave or gamma radiationSingle use applications reduce cleaning and validation requirements and costs, plus cross contamination risksSmooth, gap-free surfaces for a true seal and a secure environmentLonger life expectancy, more consistent performance, and higher purity than parts made from rubber materialsResistant to cracking and particle migrationNo taste or odor transferExcellent chemical resistance propertiesSilicone withstands temperatures ranging between -100F (-73.3C) and 400F (204.4C)Select stopper sizes available; other silicone closures custom manufacturedCertain styles available manufactured from AdvantaFlex biopharmaceutical grade TPE (thermoplastic elastomer)For use with flexible container systems, laboratory apparatus and bottles, and sampling and storage receptacles of glass, plastics, or metalAvailable with tubing installedValidation and extractables test portfolios available upon requestThe silicone and thermoplastic elastomer compounds used to make BioClosure Systems have a Master File with the U.S. Food and Drug AdministrationAdvantaPure's BioClosure Systems are manufactured from pure silicone or TPE that's free of animal-derived components. Your processes stay biologically safe.

Class VI, platinum-cured silicone elastomer comprises AdvantaPure's peristaltic pump grade silicone tubing. Ideally suited for pharmaceutical, biotech, and laboratory environments, APSPG is specially formulated to withstand repeated compression and release for consistent, dependable performance and far outlasts standard silicone tubing. APSPG platinum cured pump tubing has undergone extensive physical, chemical, and biological testing, and meets USP Class VI, FDA CFR 177.2600, ISO 10993, and European Pharmacopoeia 3.1.9 standards. APSPG Pump Grade Silicone Tubing is not intended for implantation, continuous steam applications, or elevated pressure levels. Special formulation promotes long life in pumpsExtremely flexible and resilient; hardness value of 50 Shore AOutstanding compression characteristicsSmooth surfaces offer uniform fluid flow, resistance to bacteria build-up, and consistent pump performanceAPSPG tubing is USP Class VI approvedMaterial meets FDA 21 CFR 177.2600Certified free of animal-derived ingredientsLow volatile grade suitable for pharmaceutical and biopharm applicationsMaximum operating temperature: 400F (204.4C); brittle temperature: less than -100F (-73.3C)SterilizableautoclavableImparts no taste or odor to critical streamsTranslucent for visual contact with the flowStocked in sizes from .031" through .500" I.D.Supplied double baggedDocumented lot traceable with identification on bagsDocumented quality control

Low volatile grade, platinum-cured silicone hose is clean room produced for critical pharmaceutical, biopharm, cosmetic, and food applications. Polyester yarn braiding inside the wall enhances the pressure capabilities. APSH has undergone extensive physical, chemical, and biological testing and meets USP Class VI, FDA CFR 177.2600, ISO 10993, European Pharmacopoeia 3.1.9, and 3-A standards. APSH Braid-Reinforced Silicone Hose is not intended for implantation and is not to be used for continuous steam applications.Hardness value of 65 Shore A (validatable liner: 70A; cover: 60A)Extremely flexibleGeneral temperature range: -100 F (-73.3 C) to 400 F (204.4 C)Sterilizable by autoclave, CIP, SIP, and gamma radiation processesLow volatile grade suitable for pharmaceutical and biopharm applicationsListed by the National Sanitation Foundation for food equipment materials (NSF-51)Certified free of animal-derived ingredientsResists temperature extremes, compression set, chemical attack, ozone, radiation, moisture, and environmental exposureImparts no taste or odor to critical streamsStocked in 25 and 50 ft. coilsDocumented lot traceable with identification on bagsDocumented quality controlComplete validation package available upon requestColor tracer braid available for easy identificationSupplied double bagged; other packaging options availableCustom lengths, sizes, andor special cleaning availableAPSH has a Master File with the U.S. Food and Drug Administration (#27582)

Stainless steel braided PTFE hose is constructed of virgin material with a 300 series stainless steel wire braid reinforcement jacket. The fluoropolymer core is inert and offers long flexural life, low permeability, non-flammability, and the lowest coefficient of friction of any solid material. The stainless steel braid permits higher pressure uses, reduces the possibility of kinking, and generally protects the core. Optional silicone jacketing offers protection from high temperatures during handling and keeps the outer surface clean and smooth.True Bore PTFE Smooth Core offers maximum flow; Convoluted Core offers excellent flow with enhanced flexibilityStock sizes for True Bore Smooth Core: 14 in. through 1-12 in.; Convoluted Core: 12 in. through 3 in.Hose liner meets FDA 21 CFR 177.1550, ISO 10993 Sections 5, 6, 10 and 11 and is made from USP Class VI compliant materialGeneral temperature range: -100F (-73.3C) to 450F (232.2C)Excellent chemical compatibilityResists moistureEasily cleaned or sterilized by autoclave, steam, or detergentOptional silicone jacketing makes stainless steel reinforced hose easier to handle by offering heat protectionSilicone jacketing also provides a smooth outer surface to eliminate particle entrapment for sanitary conditionsFull line of crimp fittings and custom assemblies offeredCustom lengths, sizes, other overbraiding materials, special cleaning, andor packaging is availableAdd stainless steel armor casing or cuffs for an extra layer of protection from crushing, kinking, harsh environments, and abrasion while still allowing flexibility

Premium-quality hose for elevated pressure and temperature applications in the pharmaceutical, food, and beverage processing industries is available from AdvantaPure. APEWF is specially engineered to handle a wide range of fluids and chemicals. APEWF is reinforced with a wire helix, making it suitable for suction or discharge applications. The hose offers flexibility and a smooth, sanitary inner surface for unrestricted flow for uses such as washdown stations, coolant transfer, glycol lines, and others.Excellent chemical resistance properties make this hose ideal for many demanding applicationsDesigned for suction or discharge applicationsHelical wire reinforcement helps withstand a higher level of internal pressures and maintain stated vacuum ratingsSanitary, smooth, white EPDM rubber core resists bacteria build-up and complies with FDA standards for use in food and beverage applications such as wine and beer, potable water, and fruit juicesOdorless and tasteless core fluids remain pureHandles a more extreme range of working temperatures than standard EPDM hosesOffers improved flexibility over similar fluoropolymer hosesIdeal for handling CIP solutions; may also be steam sterilized up to 302F (150C) for a maximum of 30 minutesCustom designed hose construction for flexibility easily handles bends, turns, cornersAbrasion-resistant smooth rubber coverSizes range from 34 in. (19 mm) up to 3 in. I.D. (76 mm)Full line of crimp fittings and custom assemblies offeredAdd stainless steel armor casing or cuffs for an extra layer of protection from crushing, kinking, and harsh environments while still allowing flexibilityLaser-etched stainless steel collars for quick, visual hose identification availableHose Track RF Identification and Lifecycle Analysis System available RFID tags uniquely identify individual hose assemblies, create audit trails, and track key wear-related events

Made of virgin grade FEP fluoropolymer, APFRC is overbraided with a tightly-woven fabric and double spiral steel wire to dramatically enhance its pressure-carrying capability. Its extremely smooth core offers excellent chemical resistance and is USP Class VI approved. An outer jacket of EPDM rubber provides enhanced durability and seals the hose against dirt, chemicals, or other external damage. APFRC is now available in a more flexible version. APFRC-W-FLX offers the same physical properties as the original version, however, a noticeable difference is seen in larger I.D. sizes in tight-fitting applications where added flexibility is required.Offers a smooth, non-stick interior for unrestricted fluid flowFEP core is USP Class VI approved and complies with FDA and USDA standardsResistant to kinking and chafingRated for either pressure or full vacuum (29.9 in.Hg.) applicationsGeneral temperature range: -40F (-40C) to 300F (148C)Sterilizableautoclavable (maximum internal steam temperature: 300F at 50 psi)APFRC is not to be used for continuous steam applicationsOuter rubber jacket resists rot, ozone, radiation, and environmental exposureThe FEP core imparts no taste or odor to critical streamsLong lengths available up to 100 ft. (30.5 m)Documented lot traceableDocumented quality controlFull line of 316L stainless steel sanitary fittings meeting 3-A standards and ASMEBPE specifications available; hose assemblies available through local authorized AdvantaPure fabricating distributorsAdd stainless steel armor casing or cuffs for an extra layer of protection from crushing, kinking, harsh environments, and abrasion while still allowing flexibilityCustom lengths, sizes, white covered hose, private branding, andor packaging available upon request