Dietary Supplements & Nutraceuticals #6459061

For starters Hexarelin is not your average GHRP. The structure of the amino acid is that of a hexapeptide known to help promote the release of growth hormone (GH). The mechanism of action is not yet fully understood by scientists. However, what we know is that hexarelin has the ability to act both on the pituitary gland and the hypothalamus. It is known to give the largest release of GH than any other GHRP.

Like other peptides, hexarelin has the ability to help promote more production of natural growth hormone, and it will not shut down the production of the bodys ability to produce GH. Hexarelin has been shown in studies to increase bone mineral density, mitosis and meiosis, fat loss, connective tissue strengthening, and improved skin elasticity.

Melanotan 1 (also referred to as Afamelanotide) is a synthetic peptide variant of a peptide hormone, called alpha-Melanocyte stimulating hormone or MSH that is naturally produced in the body and is responsible for stimulating melanogenesis, a peptide process for pigmentation of the skin. Alpha-MSH activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors.

As a result, Melanotan-1 sunless skin tanning effects. While Melanotan 2 and PT-141 have been studied at length as a potential remedies for the treatment of sexual dysfunction, Melanotan-1 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

AOD 9604 is a synthetic analog of the lipolytic domain of human GH. It is not a GHRH (growth hormone releasing hormone) like Modified GRF 1-29, and it is not a GHRP (growth hormone releasing peptide) like GHRP-2, or GHRP-6.AOD9604 actually acts on the reduction of excessive adipose tissues such as those in the abdominal area, increase in muscle mass, and enhances the lipid content of the body.It is also known as lipotropin and Tyr-hGH fragment, and is generally available these days as a transdermal cream or an injectable.

AOD9604 is an analog of the GRF which signals the effects of GH It is a 15-mer peptide residue of the C-terminus o to which tyrosine is added at the N-terminal end. This synthetically produced hormone is very common to weightlifters and bodybuilders because of a number of physical benefits.

Fragment (176-191) is a fat-loss peptide derived from the GH molecule, which directly initiates lipolysis and inhibits lipogenesis, but in order to better understand this peptide, it is imperative to have at least a rudimentary understanding of its parent hormone .

GH is a polypeptide which contains an amino acid sequence that is 191 amino acids in length. Frag (176-191) was developed by isolating and modifying the specific portion of the GH molecule responsible for the hormone's lipolytic and anti-lipogenic effects.

The portion of the molecule responsible for these effects is amino acids 176-191. In every sense, Frag should primarily be considered a fat loss peptide which performs these functions through the same pathways as traditional GH, but without exposing the user to the potentially undesirable side effects which may present themselves during GH administration.

Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.Its aminoacid sequence is r-l-Gly-Gly-Asp-Ala-Ser-Gly-Glu. However, it is the only neuropeptide in history whose gene is unknown, raising serious questions regarding the actual existence of this peptide in nature. Delta sleep-inducing peptide was first discovered in 1974 by the Swiss Schoenenberger-Monnier group who isolated it from the cerebral venous blood of rabbits in an induced state of sleep. It was primarily believed to be involved in sleep regulation due to its apparent ability to induce slow-wave sleep in rabbits, but studies on the subject have been contradictory.Delta-sleep-inducing peptide (DSIP)-like material has been found in human breast milk. DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids.[5] In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). It is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon. In the brain its action may be mediated by NMDA receptors. In another study Delta sleep-inducing peptide stimulated Acetyltransferase activity through 1 receptors in rats. It is unknown where DSIP is synthesized.

DISP Application :

DSIP (Delta Sleep-inducing Peptide) is a neuropeptide found in the hypothalamus, pituitary, and adrenal glands. Its isolation has allowed for extensive research which has found several possible primary and peripheral roles of this peptide. First, DSIP has been shown to induce sleep. Second, it may have benefits as an analgesic in treatment of chronic pain, sometimes as an adjunct treatment. Third, DSIP has been shown to block ACTH release and decrease levels of ACTH, stimulate LH release, and act as an inhibitor of the secretion of somatostatin. The source of production of DSIP is yet unknown; It may be produced in the central nervous system or in a peripheral organ. It is thought to pass through the blood-brain barrier (BBB) more easily than most known neuropeptides. As mentioned, DSIP has shown positive results in inducing slow-wave EEG (sleep). It has been shown to help treat narcolepsy and restore disturbed sleep patterns to normal sleep rhythms.

Creatine is creatively known as the most popular and effective nutritional supplements. Highly enough to keep up with the status of protein products, ranking "best-selling supplements" list. Was rated as "must use" the body, there are other items of athletes, such as football, basketball players, etc., want to improve their energy level, the power of people widely used.

The chemical name of creatine is methyl guanidine-acetic acid. Creatine is a natural substance found in our muscle cells, especially around skeletal muscle (about 95% of the body's creatine supply) and the remaining 5% in other parts of the body. Creatine is a metabolite produced by the body, consisting essentially of three amino acids - methionine, arginine and glycine.

Our liver has the ability to combine these three amino acids and creatine. The pancreas and kidneys also synthesize a small amount of creatine when necessary. Another source of creatine is our diet. We can also obtain creatine by using it as a dietary supplement. Although it has many different forms, the most commonly used formula for sports purposes is creatine monohydrate.

Creatine monohydrate --------Application

1). Food additives

2). Cosmetic Surfactant

3). Nutritional enhancers

4). Drug ingredients

5). Health products

Creatine monohydrate--------Benefits

1). Enhance muscle mass / strength

2). Increases muscle energy availability

3). Increased power output (multiple sets / delegates)

4). Weight gain