ZH Chemical company

Hangzhou, United States

Pantothenic acid is widely found in various plants and animals, and is also an essential vitamin for our human body.

Pantothenic acid is a yellowish, viscous substance, and its aqueous solution is neutral or slightly alkaline.Pantothenic acid has good thermal stability in neutral solution, but it is not easy to be oxidized or reduced, but it is easy to be destroyed by acid, alkali and dry heat conditions to form calcium salt of pantothenic acid.

Pantothenic acid has the important function of making antibodies in physiology, which can play the role of protecting skin, hair and blood. If human body lacks acid, insomnia, nausea, fatigue, dermatitis and abnormal performance of rapid heartbeat will occur.

Vitamin B5, also known as pantothenic acid, is a member of the B vitamin group. It is also a water-soluble vitamin, consisting of 2, 4-dihydroxyl-3, 3-dimethyl butyric acid, bound by an amide bond of -alanine and widely distributed in animals and plants.Vitamin B5 is found in foods that are known to contain it, and if animals or people lack it, it can cause anemia, skin inflammation, kidney damage, stunted growth, and other injuries.

The active form of vitamin B5 is coenzyme A, which, as the carrier of acyl group in vivo, mainly plays A role in the oxidation of fat and pyruvate.

gardenia is a traditional chinese medicinal material with a very long application history in china, and it is widely used. However, with the development of technology, the application of gardenia is also continuously developed and penetrated. With more uses of gardenia, the substrate of pharmacological action of gardenia is increasingly clear. Gardenoside is one of the most active gardenia ingredients, but if we need to purchase gardenoside, how do we determine the amount of gardenoside?

currently, the methods used to determine gardenoside content are high performance liquid chromatography (hplc), thin layer scanning (tlc) and thin layer - uv spectrophotometry. When using hplc, gardenoside's hydrophilicity is used, and the mobile phase typically uses phosphate aqueous solvents and polar solvents, compared to the standard gardenoside chromatograms. Thin-layer scanning is used because gardenoside has fluorescent absorption spots at 254m in the uv region. Using this property to locate under fluorescent lamps, uv scanning is simple, stable and reproducibility. For the determination of gardenoside by tlc-uv spectrophotometry, a suitable silica gel thin layer plate and an unfolding agent are required. The unfolding agent can use chloroform: methanol =3:1, and the wavelength obtained is 237 nm. Gardenoside sample solution is required to be prepared for determination.